Every Cell has a Story to Tell

“Today, our MaxOne System plays a central role in our work. In fact, it has become a defining element of our research. It allows us to grow organoid-derived neural networks directly on the array surface and record their activity over long periods. This enables us to observe temporal-spatial dynamics, correlations, and sequential patterns of activity, all within a single, integrated system. Given the complexity of the networks we’re studying, the fact that the technology is also easy to use makes it even more valuable.”

"MaxOne opened so many doors in regards to questions of brain wiring, genetics, drug discovery, access to circuitry through organoids, which could not be addressed in any other way."

“If you have one electrode covered by many neurons, you acquire average information, which is not enough for specific computing conditions. What we really aim is high resolution at a single-neuron level, something we can achieve with MaxOne HD-MEA.”

“Unlike other commercially available MEA systems, MaxTwo has an outstanding capability to measure and track action potentials in single neurons due to how the electrodes are arrayed in such a high density manner."

“The MaxOne HD-MEA Chips allowed us to align neural activity to histology at comparable resolution. Also, it enabled us to study network activity and the structured spatial dynamics across the sub-regions of the hippocampus during seizure-like activity and optogenetic silencing.”

“The flat electrodes make attaching PDMS structures much easier, leading to a simple, low-risk protocol - exactly what you want in the lab. Plus, the excellent signal-to-noise ratio was key throughout my project for detecting axons with very low amplitude signals.”